He's had bit parts in over 65 television shows and films (including "American Pie" and "Spider Man") and yesterday was propelled to international fame when he starred in a spot aired during the Super Bowl for GoDaddy, a domain name registration company.
In the spot (above), Jesse, as the company's 'nerdy' side, had a relatively long french kiss with supermodel Bar Rafaeli, the company's 'sexy' side.
So what exactly has happened to Jesse since the spot aired? Well, according to Jesse, he's become a sex symbol.
And the interest isn't just limited to online, with Jesse being approached by female fans in the street. "I have girls run up to me and take pictures with me, tweet me for dates."
Jesse has also had an explosion of interest in his acting work, with his agent's phone in meltdown. "There are lots of inquiries coming in to my agent and manager, their phone has been ringing off the hook, but they are really letting me enjoy the moment right now."
In other Jesse news, you may recognise him as the "World's Greatest Extra". A video tribute made by a fan for Jesse has had over 3 million hits on Youtube.Related: World's Greatest Extra